reproductive immunology

The failure to conceive is often due to immunological problems that can lead to very early rejection of the embryo. This commonly occurs in conditions such as endometriosis, an under-active thyroid gland or in cases of "unexplained infertility. It has been estimated that an immune factor may be involved in up to 20% of couples with otherwise unexplained infertility. For a successful pregnancy to occur, your immune system must allow it. If this special immunity fails, then the process by which the embryo implants and is not rejected falters. Successful implantation may therefore not occur and if implantation starts, the risk of miscarriage may increase. Our Reproductive Immunology Programme helps couples globally with recurrent IVF/ICSI failures and recurrent miscarriage.

indications for testing reproductive immunology

  • Unexplained infertility
  • Repeated miscarriages
  • Poor egg production from a stimulated cycle (less than 6 eggs)
  • One blighted ovum
  • Previous immune problems (ANA positive, rheumatoid arthritis, and/or lupus)
  • Previous pregnancies that have shown retarded fetal growth
  • One living child and repeat miscarriages while attempting to have a second child

tests for immunological screening

IVIG Treatment Screen

  • Day 3 Inhibin B
  • Anti-Phospholipid Antibodies (APA)
  • Anti Cardiolipin Antibodies (ACA)
  • Natural Killer Cells
  • Anti-Ovarian Antibodies (AOA)
  • Anti-Sperm Antibodies (ASA)
  • Lupus Anticoagulant (LAC)
  • Anti-Nuclear Antibodies Screen (ANA)
  • Anti-Microsomal Antibodies
  • Leukocyte Antibody Detection (LAD)
  • HLA DQ ALPHA and BETA
  • Embryo Toxic Factor (ETF)
  • Sperm Penetration Assay (SPA)
  • Acrosome Reaction (MCP, CD46)
  • Chromosome Analysis
  • CD 3
  • CD 19
  • CD 16
  • CD 56
  • TNF Alpha
  • Integrin ? Biopsy

Endometrial Receptivity Testing Panel

  • Cyclin E
  • P27
  • MAG
are you facing?

failed IVF cycles

Moolchand is a leader in fertility treatments providing a range of ...

inability to conceive

If you are trying to conceive and are challenged by years of...

unexplained infertility

Unexplained infertility is quite common. About 10% of couples,...